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KMID : 1101420200520020128
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Korean Journal of Clinical Laboratory Science
2020 Volume.52 No. 2 p.128 ~ p.135
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Molecular Subtyping of Methicillin-Resistant Staphylococcus aureus Isolated from Patients’ Nasal Cavity
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Kim Sang-Ha
Park Sung-Bae
Park Hee-Chul
Kim Jun-Seong
Kim Jung-Ho
Lee Ji-Young
Lim Jae-Won
Kim Young-Kwon
Kim Sung-Hyun
Kim Sung-Hyun
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Abstract
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Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterium that causes infections in different parts of the body and causes skin and soft tissue infections (SSTI). The present study examined the antimicrobial resistance patterns and molecular epidemiological characteristics of MRSA isolated from nasal swabs in clinical patients. SCCmec type of MRSA isolates from clinical patients were analyzed: 24 cases were SCCmec type-II; two cases were type-II/IVa; one case was type-II/V; one case was type-IVa; 11 cases were not-typeable. The mec complex type of MRSA isolates from clinical patients were analyzed: 29 cases were mec complex type A, and 10 cases were not-typeable, but type B was not found in the present study. In conclusion, SCCmec type-II and mec complex type A were the most dominant MRSA subtypes among the MRSA isolates from a nasal swab of patients, and the results were similar to other studies on hospital-acquired MRSA (HA-MRSA). These results can not only provide basic data for hospital infection management but also be a good guideline for MRSA infections in the Republic of Korea.
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KEYWORD
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Infection control, Methicillin-resistant Staphylococcus aureus, Molecular epidemiology, Nasal cavity
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